Lab Vision Corporation

Welcome to Lab Vision Corporation, your premier source for unrivaled immunohistochemistry instruments, reagents, and cutting-edge life science products.

IHC Detection Systems

UltraVision Ancillary Products: (View Products)

Immunohistochemistry Detection Systems:

MultiVision : (View Products) ^New

MultiVision Polymer Detection System is a simple and robust one-step polymer detection system for visualization of two antigens simultaneously in blue and red. A primary antibody cocktail of choice may be used in conjunction with ready-to-use MultiVision polymer cocktail. This cocktail is specially formulated from MultiVision polymers that provide increased sensitivity, time-savings, and detection simplicity. The MultiVision AP and HRP polymers are innovative, patented technologies consisting of smaller amino acid polymer subunits that minimize conflicts in binding the target protein. The smaller polymer allows for decreased binding conflicts resulting in more consistent staining and better signal amplification. Ultimately, this gives the user higher sensitivity and antibody efficiency as well as better signal-to-noise ratios. This system is biotin-free, eliminating background staining found with traditional biotin-based methods. The MultiVision Polymer Detection System yields high quality double staining in less than 2 hours on formalin-fixed and paraffin-embedded tissue sections. For optimal interpretation of results, appropriate positive and negative controls must be included.

UltraVision ONE : (View Products)

UltraVision one is the latest in polymer labeling technology. This robust, easy-to-use, biotin-free system offers increased sensitivity, time savings and detection simplicity. It delivers crisp stains with both rabbit and mouse primary antibodies and is offered in both HRP and AP formats. It consists of smaller amino acid polymer subunits that minimize conflicts in binding the target protein. Decreased binding conflicts result in more consistent staining and better signal amplification. Ultimately, this gives the user higher sensitivity and antibody efficiency. UltraVision ONE offers considerable time savings, as antibody enhancers are not required, and protein blocking is optional. It is scalable from automation to manual bench top applications and may be used with a compatible chromogen of choice. The polymer system also eliminates background staining found with tranditional biotin-based systems.timal interpretation of results, appropriate positive and negative controls must be included.

UltraVision: (View Products)

UltraVision is Lab Vision's standard and most economical detection system. It produces a high signal-to-noise ratio and high sensitivity at an economical price. UltraVision is based on labeled streptavidin-biotin technology. Specifically, the secondary is comprised of a biotinylated "spacer-arm" anti-mouse and/or anti-rabbit IgG conjugate. The spacer arm technology allows for more efficient spatial binding of tertiary streptavidin conjugate component by eliminating steric hindrance. The tertiary component, streptavidin, is enzyme-bound (HRP or alkaline phosphatase). Finally, antibody detection is completed by developing with a chromogen-substrate mixture. The product is ready-to-use and does not require secondary and tertiary component mixing or the long incubation times that are common with Avidin-Biotin-Complex detection methods. Furthermore, UltraVision is stable for at least one year.

UltraVision Plus: (View Products)

UltraVision Plus is a traditional detection system reformulated for rapid IHC staining using purified and balanced components. Our biotinylated "spacer-arm" conjugate is a pre-absorbed goat anti-mouse and anti-rabbit cocktail that links to a streptavidin-enzyme conjugate. This carries carefully selected, high-reactivity enzymes for signal generation using our freshly prepared, well-established chromogens of your choice to provide superb, clean signals. UltraVision Plus is extremely efficient. It has been designed to give rapid results for urgent work and to optimize throughput on automated systems such as our Autostainers LV1 and LV2D. UltraVision Plus follows traditional methods with three simple 5-minute incubation steps. UltraVision Plus is an ideal companion to Lab Vision's new 10-minute incubation Rabbit Monoclonal primary antibodies.

UltraVision LP: (View Products)

UltraVision LP uses the latest in polymer technology. Polymeric labeling systems have been shown to provide simpler, problem-free detection with significant increases in sensitivity. Lab Vision's new generation polymer system uses a smaller polymer subunit to enhance the labeling of target proteins by minimizing the molecular conflicts common with larger polymers. Enhanced binding produces better signal amplification, consistent performance irrespective of the target location (membrane, nuclear, or cytoplasmic), and ultimately greater sensitivity. With UltraVision LP, you use less antibody, eliminate avidin/biotin background problems, improve signal-to-noise ration, and increase sensitivity for the most economical use of your valuable antibodies.

UltraVision LP Value: (View Products)

UltraVision LP Value is a polymer system based on the same technology used in the UltraVision LP, at a more economical price. it offers high sensitivity and signal amplification comparable to UltraVision LP. As with UltraVision LP, you use less antibody, eliminate avidin/biotin background problems, improve signal-to-noise ratio, and increase sensitivity.

UltraVision Mouse-on-Mouse: (View Products)

Ultra Vision Mouse-on-Mouse is a research detection system for visualizing mouse-hosted primary antibodies on mouse tissues. Based on Lab Vision's UltraVision detection system (see above), a proprietary blocking step is added to the procedure to reduce Immunological cross-reactivity innate to the system. The additional blocking step considerably eliminates non-target detection system binding thus decreasing unwanted background staining. Often, when attempting to visualize mouse primary IgG's on mouse tissues, ordinary methods not only bind to the primary antibodies, but to naturally occurring mouse IgG's as well. The UltraVision Mouse-on-Mouse eliminates non-target detection system binding for a cleaner, more useful IHC stain.